Together with Prof. Steven Abbott and Dr. Charles Hansen, VLCI promotes HSP for a wide range of applications.
Solubility of a product is represented as a sphere and characterized by three Hansen Solubility Parameters (HSP):
The HSP theory is based on the “like seeks like” principle, with likeness measured by the HSP distance metric. The critical conditions for solubility are found within a spherical region of HSP space, around the centre. Therefore, inclusions in the sphere, or overlapping spheres, predict solubility or compatibility.
HSP determination is a powerful and practical way to understand, predict and improve:
HSPs allow strong predictions for smart and efficient ingredient matching.
The solubility (or dispersibility) of a product is assessed within a standardized set of solvents with known HSPs, spread over the 3-dimensional HSP space. Solvents and products are automatically dispensed via the gravimetric dispensing unit of our High Throughput platform. The solubility is ranked from 1 (excellent) to 6 (very poor). Based on these scores, the HSPiP software generates the solubility sphere of the tested product.
VLCI offers HSP expertise combined with High Throughput capabilities to deliver fast, practical and accurate results.